Medical Dosimetry
Volume 32, Issue 3 , Pages 172-180 , Autumn 2007

Does Intensity Modulation Improve Healthy Tissue Sparing in Stereotactic Radiosurgery of Complex Arteriovenous Malformations?

  • Brenda Clark, Ph.D.

      Affiliations

    • Department of Radiation Oncology, British Columbia Cancer Agency, Vancouver, BC, Canada
    • Corresponding Author InformationReprint requests to: Brenda Clark, Ph.D., The Ottawa Hospital Regional Cancer Centre, Department of Medical Physics, 501 Smyth Road, Box #927, Ottawa, Ontario K1H 8L6, Canada.
    • ,
  • Michael McKenzie, M.D.

      Affiliations

    • Department of Radiation Oncology, British Columbia Cancer Agency, Vancouver, BC, Canada
    • ,
  • James Robar, Ph.D.

      Affiliations

    • Department of Radiation Oncology, British Columbia Cancer Agency, Vancouver, BC, Canada
    • ,
  • Emily Vollans, M.Sc.

      Affiliations

    • Department of Radiation Oncology, British Columbia Cancer Agency, Vancouver, BC, Canada
    • ,
  • Charlie Candish, M.D.

      Affiliations

    • Department of Radiation Oncology, British Columbia Cancer Agency, Vancouver, BC, Canada
    • ,
  • Brian Toyota, M.D.

      Affiliations

    • Department of Neurosurgery, Vancouver General Hospital, Vancouver, BC, Canada
    • ,
  • Andrew Lee, M.D.

      Affiliations

    • Department of Neurosurgery, Vancouver General Hospital, Vancouver, BC, Canada
    • ,
  • Roy Ma, M.D.

      Affiliations

    • Department of Radiation Oncology, British Columbia Cancer Agency, Vancouver, BC, Canada
    • ,
  • Karen Goddard, M.D.

      Affiliations

    • Department of Radiation Oncology, British Columbia Cancer Agency, Vancouver, BC, Canada
    • ,
  • Sara Erridge, M.D.

      Affiliations

    • Department of Radiation Oncology, British Columbia Cancer Agency, Vancouver, BC, Canada

Received 24 November 2006 ,Accepted 14 December 2006.

References 

  1. Leksell L. The stereotaxic method and radiosurgery of the brain. Acta Chir. Scand. 1951;102:316–319
  2. Steinberg GK, Fabrikant JI, Marks MP, et al. Stereotactic heavy-charged-particle Bragg-peak radiation for intracranial arteriovenous malformations. N. Engl. J. Med. 1990;323:96–101
  3. Lunsford LD, Kondziolka D, Flickinger JC, et al. Stereotactic radiosurgery for arteriovenous malformations of the brain. J. Neurosurg. 1991;75:512–514
  4. Miyawaki L, Dowd C, Wara W, et al. Five year results of linac radiosurgery for arteriovenous malformations: Outcome for large AVMs. Int. J. Radiat. Oncol. Biol. Phys. 1999;44:1089–1106
  5. Maruyama K, Kawahara N, Shin M, et al. The risk of hemorrhage after radiosurgery for cerebral arteriovenous malformations. N. Engl. J. Med. 2005;352:146–153
  6. Schwartz M, Sixel K, Young C, et al. Prediction of obliteration of arteriovenous malformations after radiosurgery: The Obliteration Prediction Index. Can. J. Neurol. Sci. 1997;24:106–109
  7. Flickinger JC, Schell M, Larson DA. An integrated logistic formula for prediction of complications from radiosurgery. Int. J. Radiat. Oncol. Biol. Phys. 1990;19:143–148
  8. Flickinger JC, Kondziolka D, Maitz AH, et al. Analysis of neurological sequelae from radiosurgery of arteriovenous malformations: How location affects outcome. Int. J. Radiat. Oncol. Biol. Phys. 1998;40:273–278
  9. Clark BG, Robar JL, Nichol AM. Analysis of treatment parameters for conformal shaped field stereotactic irradiation: Comparison with non-coplanar arcs. Phys. Med. Biol. 2001;46:3089–3103
  10. De Salles AA, Pedroso AG, Medin P, et al. Spinal lesions treated with Novalis shaped beam intensity-modulated radiosurgery and stereotactic radiotherapy. J. Neurosurg. 2004;101(Suppl 3):435–440
  11. Solberg TD, Boedeker KL, Fogg R, et al. Dynamic arc radiosurgery field shaping: A comparison with static field conformal and noncoplanar circular arcs. Int. J. Radiat. Oncol. Biol. Phys. 2001;49:1481–1491
  12. Studholme C, Hill DL, Hawkes DJ. Automated 3-D registration of MR and CT images of the head. Med. Image Anal. 1996;1:163–175
  13. Petric MP, Clark BG, Robar JL. A comparison of two commercial treatment-planning systems to IMRT. J. Appl. Clin. Med. Phys. 2005;6:63–80
  14. Cardinale RM, Benedict SH, Wu Q, et al. A comparison of three stereotactic radiotherapy techniques: ARCS vs. noncoplanar fixed fields vs. intensity modulation. Int. J. Radiat. Oncol. Biol. Phys. 1998;42:431–436
  15. Kramer BA, Wazer DE, Engler MJ, et al. Dosimetric comparison of stereotactic radiosurgery to intensity modulated radiotherapy. Radiat. Oncol. Invest. 1998;6:18–25
  16. Singh RR, Ayyangar KM, Shen B, et al. Comparative study between IMRT with NOMOS BEAK and linac-based radiosurgery in the treatment of intracranial lesions. Med. Dosim. 2001;26:47–53
  17. Benedict SH, Cardinale RM, Wu Q, et al. Intensity-modulated stereotactic radiosurgery using dynamic micro-multileafcollimation. Int. J. Radiat. Oncol. Biol. Phys. 2001;50:751–758
  18. Sankaranarayanan V, Ganesan S, Oommen S, et al. Study on dosimetric parameters for stereotactic radiosurgery and intensity-modulated radiotherapy. Med. Dosim. 2003;28:85–90
  19. Perks JR, St George EJ, El Hamri K, et al. Stereotactic radiosurgery XVI: Isodosimetric comparison of photon stereotactic radiosurgery techniques (gamma knife vs. micromultileaf collimator linear accelerator) for acoustic neuroma—and potential clinical importance. Int. J. Radiat. Oncol. Biol. Phys. 2003;57:1450–1459
  20. Georg D, Dieckmann K, Bogner J, et al. Impact of a micromultileaf collimator on stereotactic radiotherapy of uveal melanoma. Int. J. Radiat. Oncol. Biol. Phys. 2003;55:881–891
  21. Verhey LJ. Comparison of three-dimensional conformal radiation therapy and intensity-modulated radiation therapy systems. Semin. Radiat. Oncol. 1999;9:78–98
  22. Mestrovic A, Clark BG. Geometric parameter analysis to predetermine optimal radiosurgery technique for the treatment of arteriovenous malformation. Int. J. Radiat. Oncol. Biol. Phys. 2005;63:940–951
  23. Loeffler JS, Niemierko A, Chapman PH. Second tumors after radiosurgery: Tip of the iceberg or a bump in the road?. Neurosurgery. 2003;52:1436–1440
  24. Narayanan KR, Howlett T, Lincoln NB, et al. Evaluation of the effect of radiotherapy for pituitary tumours on cognitive function and quality of life. Clin. Oncol. (R. Coll. Radiol.). 2004;16:233–237
  25. Steinvorth S, Wenz F, Wildermuth S, et al. Cognitive function in patients with cerebral arteriovenous malformations after radiosurgery: Prospective long-term follow-up. Int. J. Radiat. Oncol. Biol. Phys. 2002;54:1430–1437
  26. Kulik C, Caudrelier JM, Vermandel M, et al. Conformal radiotherapy optimization with micromultileaf collimators: Comparison with radiosurgery techniques. Int. J. Radiat. Oncol. Biol. Phys. 2002;53:1038–1050

PII: S0958-3947(06)00179-8

doi: 10.1016/j.meddos.2006.12.002

Medical Dosimetry
Volume 32, Issue 3 , Pages 172-180 , Autumn 2007

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