Medical Dosimetry
Volume 32, Issue 3 , Pages 204-210 , Autumn 2007

Role of Ovarian Transposition Based on the Dosimetric Effects of Craniospinal Irradiation on the Ovaries: A Case Report

Presented at the 48th Annual Meeting of the American Society of Therapeutic Radiology and Oncology; Philadelphia, PA; 2006.

  • James D. Mitchell, M.D.

      Affiliations

    • New York University School of Medicine, New York, NY
    • ,
  • Christine Hitchen, M.S.

      Affiliations

    • New York University School of Medicine, New York, NY
    • ,
  • Maria T. Vlachaki, M.D., Ph.D.

      Affiliations

    • New York University School of Medicine, New York, NY
    • Department of Radiation Oncology, Wayne State University, Detroit, MI
    • Corresponding Author InformationReprint requests to: Maria T. Vlachaki, M.D., Ph.D., Wayne State University, Department of Radiation Oncology, 540 E. Canfield, 1212 Scott Hall, Detroit, MI 48201.

Received 5 February 2007 ,Accepted 5 February 2007.

References 

  1. Husseinzadeh N, Nahhas WA, Velkley DE, et al. The preservation of ovarian function in young women undergoing pelvic radiation therapy. Gynecol. Oncol. 1984;18:373–379
  2. Wallace WH, Shalet SM, Tetlow LJ, et al. Ovarian function following the treatment of childhood acute lymphoblastic leukaemia. Med. Pediatr. Oncol. 1993;21:333–339
  3. Allen JC, Donahue B, DaRosso R, et al. Hyperfractionated craniospinal radiotherapy and adjuvant chemotherapy for children with newly diagnosed medulloblastoma and other primitive neuroectodermal tumors. Int. J. Radiat. Oncol. Biol. Phys. 1996;36:1155–1161
  4. Ray GR, Trueblood HW, Enright LP, et al. Oophoropexy: A means of preserving ovarian function following pelvic megavoltage radiotherapy for Hodgkin’s disease. Radiology. 1970;96:175–180
  5. Trueblood HW, Enright LP, Ray GR, et al. Preservation of ovarian function in pelvic radiation for Hodgkin’s disease. Arch. Surg. 1970;100:236–237
  6. Grigsby PW, Russell A, Bruner D, et al. Late injury of cancer therapy on the female reproductive tract. Int. J. Radiat. Oncol. Biol. Phys. 1995;31:1281–1299
  7. Peck WS, McGreer JT, Kretzschmar NR, et al. Castration of the female by irradiation: The results in 334 patients. Radiology. 1940;34:176–186
  8. Shalet SM, Beardwell CG, Jones PH, et al. Ovarian failure following abdominal irradiation in childhood. Br. J. Cancer. 1976;33:655–658
  9. Wallace WH, Thomson AB, Kelsey TW. The radiosensitivity of the human oocyte. Hum. Reprod. 2003;18:117–121
  10. Wallace WH, Thomson AB, Saran F, et al. Predicting age of ovarian failure after radiation to a field that includes the ovaries. Int. J. Radiat. Oncol. Biol. Phys. 2005;62:738–744
  11. Byrne J, Fears TR, Gail MH, et al. Early menopause in long-term survivors of cancer during adolescence. Am. J. Obstet. Gynecol. 1992;166:788–793
  12. Whitehead E, Shalet SM, Blackledge G, et al. The effect of combination chemotherapy on ovarian function in women treated for Hodgkin’s disease. Cancer. 1983;52:988–993
  13. Meirow D. Ovarian injury and modern options to preserve fertility in female cancer patients treated with high dose radio-chemotherapy for hemato-oncological neoplasias and other cancers. Leuk. Lymphoma. 1999;33:65–76
  14. Hamre MR, Robison LL, Nesbit ME, et al. Effects of radiation on ovarian function in long-term survivors of childhood acute lymphoblastic leukemia: A report from the Childrens Cancer Study Group. J. Clin. Oncol. 1987;5:1759–1765
  15. Schuck A, Hamelmann V, Bramswig JH, et al. Ovarian function following pelvic irradiation in prepubertal and pubertal girls and young adult women. Strahlenther. Onkol. 2005;181:534–539
  16. Kim SS. Fertility preservation in female cancer patients: Current developments and future directions. Fertil. Steril. 2006;85:1–11
  17. Yuh GE, Loredo LN, Yonemoto LT, et al. Reducing toxicity from craniospinal irradiation: Using proton beams to treat medulloblastoma in young children. Cancer J. 2004;10:386–390
  18. St Clair WH, Adams JA, Buesm M, et al. Advantage of protons compared to conventional X-ray or IMRT in the treatment of a pediatric patient with medulloblastoma. Int. J. Radiat. Oncol. Biol. Phys. 2004;58:727–734
  19. Le Floch O, Donaldson SS, Kaplan HS. Pregnancy following oophoropexy and total nodal irradiation in women with Hodgkin’s disease. Cancer. 1976;38:2263–2268
  20. Clough KB, Goffinet F, Labib A, et al. Laparoscopic unilateral ovarian transposition prior to irradiation: Prospective study of 20 cases. Cancer. 1996;77:2638–2645
  21. Visvanathan DK, Cutner AS, Cassoni AM, et al. A new technique of laparoscopic ovariopexy before irradiation. Fertil. Steril. 2003;79:1204–1206
  22. Williams RS, Littell RD, Mendenhall NP. Laparoscopic oophoropexy and ovarian function in the treatment of Hodgkin disease. Cancer. 1999;86:2138–2142
  23. Scott SM, Schlaff W. Laparoscopic medial oophoropexy prior to radiotherapy in an adolescent with Hodgkin’s disease. J. Pediatr. Adolesc. Gynecol. 2005;18:355–357
  24. Farber LA, Ames JW, Rush S, et al. Laparoscopic ovarian transposition to preserve ovarian function before pelvic radiation and chemotherapy in a young patient with rectal cancer. MedGenMedn. 2005;7:66

PII: S0958-3947(07)00043-X

doi: 10.1016/j.meddos.2007.02.004

Medical Dosimetry
Volume 32, Issue 3 , Pages 204-210 , Autumn 2007

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