Medical Dosimetry
Volume 32, Issue 4 , Pages 299-304 , Winter 2007

Clinical Implementation of Tangential Field Intensity Modulated Radiation Therapy (IMRT) Using Sliding Window Technique and Dosimetric Comparison with 3D Conformal Therapy (3DCRT) in Breast Cancer

  • Raj N. Selvaraj, M.S., D.A.B.R., D.A.B.M.P.

      Affiliations

    • Department of Radiation Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, PA
    • University of Pittsburgh School of Medicine, Pittsburgh, PA
    • Corresponding Author InformationReprint requests to: Raj N. Selvaraj, M.S., D.A.B.R., D.A.B.M.P., Senior Medical Physicist, Clinical Assistant Professor, Department of Radiation Oncology, Medical Physics Division, UPMC - Passavant Hospital, 9100 Babcock Boulevard, Pittsburgh, PA 15237-6913.
    • ,
  • Sushil Beriwal, M.D.

      Affiliations

    • Department of Radiation Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, PA
    • University of Pittsburgh School of Medicine, Pittsburgh, PA
    • ,
  • Roya J. Pourarian, R.T.T., B.S.R.T.

      Affiliations

    • Department of Radiation Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, PA
    • ,
  • Ron J. Lalonde, Ph.D.

      Affiliations

    • D3 Advanced Radiation Planning Services, Pittsburgh, PA
    • ,
  • Alex Chen, M.D.

      Affiliations

    • Department of Radiation Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, PA
    • University of Pittsburgh School of Medicine, Pittsburgh, PA
    • ,
  • Kiran Mehta, M.D.

      Affiliations

    • Department of Radiation Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, PA
    • University of Pittsburgh School of Medicine, Pittsburgh, PA
    • ,
  • Gwendolyn Brunner, M.S.

      Affiliations

    • Department of Radiation Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, PA
    • University of Pittsburgh School of Medicine, Pittsburgh, PA
    • ,
  • Kathy A. Wagner, C.M.D.

      Affiliations

    • D3 Advanced Radiation Planning Services, Pittsburgh, PA
    • ,
  • Ning J. Yue, Ph.D.

      Affiliations

    • Department of Radiation Oncology, The Cancer Institute of New Jersey, New Brunswick, NJ
    • ,
  • Saiful M. Huq, Ph.D.

      Affiliations

    • Department of Radiation Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, PA
    • University of Pittsburgh School of Medicine, Pittsburgh, PA
    • ,
  • Dwight E. Heron, M.D.

      Affiliations

    • Department of Radiation Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, PA
    • University of Pittsburgh School of Medicine, Pittsburgh, PA

Received 9 January 2007 ,Accepted 9 March 2007.

References 

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  12. Lo YC, Yasuda G, Fitzgerald TJ. Intensity modulation for breast treatment using static multi-leaf collimators. Int. J. Radiat. Oncol. Biol. Phys. 2000;46:187–194
  13. Kestin LL, Sharpe MB, Frazier RC, et al. Intensity modulation to improve dose uniformity with tangential breast radiotherapy: Initial clinical experience. Int. J. Radiat. Oncol. Biol. Phys. 2000;48:1559–1668
  14. Fraass B, Doppke K, Hunt M, et al. American Association of Physicists in Medicine Radiation Therapy Committee Task Group 53: Quality assurance for clinical radiotherapy treatment planning. Med. Phys. 1998;25:1773–1829
  15. Evans PM, Donovan EM, Partridge M, et al. The delivery of intensity modulated radiotherapy to the breast using multiple static fields. Radiother. Oncol. 2000;57:79–89
  16. Chui CS, Hong L, Hunt M, et al. A simplified intensity modulated radiation therapy technique for the breast. Med. Phys. 2002;29:522–529
  17. Chang SX, Deschesne KM, Cullip TJ, et al. A comparison of different intensity modulation treatment techniques for tangential breast irradiation. Int. J. Radiat. Oncol. Biol. Phys. 1999;45:1305–1314
  18. Vicini FA, Sharpe M, Martinez A, et al. Optimizing breast cancer treatment efficacy with intensity-modulated radiotherapy. Int. J. Radiat. Oncol. Biol. Phys. 2002;54:1336–1344
  19. Li JS, Freedman GM, Price R, et al. Clinical implementation of intensity-modulated tangential beam irradiation for breast cancer. Med. Phys. 2004;31:1023–1031
  20. Freedman GM, Anderson PR, Li J, et al. Intensity modulated radiation therapy (IMRT) decreases acute skin toxicity for women receiving radiation for breast cancer. Am. J. Clin. Oncol. 2006;29:66–70
  21. Bhatnagar AK, Brandner E, Sonnik D, et al. Intensity modulated radiation therapy (IMRT) reduces the dose to the contralateral breast when compared to the conventional tangential fields for primary breast irradiation. Breast Cancer Res. Treat. 2005;96:41–46
  22. Woo TC, Pignol JP, Rakovitch E, et al. Body radiation exposure in breast cancer radiotherapy: Impact of breast IMRT and virtual wedge compensation techniques. Int. J. Radiat. Oncol. Biol. Phys. 2006;1:52–58
  23. George R, Keall PJ, Kini VR, et al. Quantifying the effect of intrafraction motion in during breast IMRT planning and dose delivery. Med. Phys. 2003;30:552–562
  24. Ding M, Li J, Deng J, et al. Dose correlation for thoracic motion in radiation therapy of breast cancer. Med. Phys. 2003;30:2520–2529

PII: S0958-3947(07)00054-4

doi: 10.1016/j.meddos.2007.03.001

Medical Dosimetry
Volume 32, Issue 4 , Pages 299-304 , Winter 2007

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