Medical Dosimetry
Volume 34, Issue 3 , Pages 233-242 , Autumn 2009

Adaptive Radiation Therapy for Localized Mesothelioma with Mediastinal Metastasis Using Helical Tomotherapy

  • James Renaud

      Affiliations

    • Department of Physics and Engineering, London Regional Cancer Program, London Health Sciences Centre, London, Ontario, Canada
  • ,
  • Slav Yartsev, Ph.D.

      Affiliations

    • Department of Physics and Engineering, London Regional Cancer Program, London Health Sciences Centre, London, Ontario, Canada
    • Department of Oncology, The University of Western Ontario, London, Ontario, Canada
    • Corresponding Author InformationReprint requests to: Slav Yartsev, Ph.D., LRCP/LHSC, 790 Commissioners Road, East, London, Ontario N6A 4L6, Canada
  • ,
  • A. Rashid Dar, M.D., F.R.C.P.C.

      Affiliations

    • Department of Radiation Oncology, London Regional Cancer Program, London Health Sciences Centre, London, Ontario, Canada
    • Department of Oncology, The University of Western Ontario, London, Ontario, Canada
  • ,
  • Jake Van Dyk, M.Sc., F.C.C.P.M.

      Affiliations

    • Department of Physics and Engineering, London Regional Cancer Program, London Health Sciences Centre, London, Ontario, Canada
    • Department of Oncology, The University of Western Ontario, London, Ontario, Canada

Received 2 July 2008 ,Accepted 23 October 2008.

References 

  1. Miles EF, Larrier NA, Kelsey CR, et al. Intensity-modulated radiotherapy for resected mesothelioma: The Duke experience. Int. J. Radiat. Oncol. Biol. Phys. 2008;71:1143–1150
  2. Krayenbuehl J, Oertel S, Davis JB, et al. Combined photon and electron three-dimensional conformal versus intensity-modulated radiotherapy with integrated boost for adjuvant treatment of malignant pleural mesothelioma after pleuropneumonectomy. Int. J. Radiat. Oncol. Biol. Phys. 2007;69:1593–1599
  3. Perez CA, Pajak TF, Rubin P. Long-term observations of the patterns of failure in patients with unresectable non-oat cell carcinoma of the lung treated with definitive radiotherapy: Report of the Radiation Therapy Oncology Group. Cancer. 1987;59:1874–1881
  4. Siker ML, Tomë WA, Mehta MP. Tumor volume changes on series imaging with megavoltage CT for non-small-cell lung cancer during intensity-modulated radiotherapy: How reliable, consistent, and meaningful is the effect?. Int. J. Radiat. Oncol. Biol. Phys. 2006;66:135–141
  5. Kong FM, Hayman JA, Griffith KA, et al. Final toxicity results of a radiation-dose escalation study in patients with non-small-cell lung cancer (NSCLC): Predictors for radiation pneumonitis and fibrosis. Int. J. Radiat. Oncol. Biol. Phys. 2006;65:1075–1086
  6. Allen AM, Schofield D, Hacker F, et al. Restricted field IMRT dramatically enhances IMRT planning for mesothelioma. Int. J. Radiat. Oncol. Biol. Phys. 2007;69:1587–1592
  7. Allen AM, Czerminska M, Jänne PA, et al. Fatal pneumonitis associated with intensity-modulated radiation therapy for mesothelioma. Int. J. Radiat. Oncol. Biol. Phys. 2006;65:640–645
  8. Sterzing F, Sroka-Perez G, Schubert K, et al. Evaluating target coverage and normal tissue sparing in the adjuvant radiotherapy of malignant pleural mesothelioma: Helical tomotherapy compared with step-and-shoot IMRT. Radiother. Oncol. 2008;86:251–257
  9. Mehta M, Scrimger R, Mackie R, et al. A new approach to dose escalation in non-small cell lung cancer. Int. J. Radiat. Oncol. Biol. Phys. 2001;49:23–33
  10. Lieskovsky YC, Koong A, Fisher G, et al. Phase I dose escalation study of CyberKnife stereotactic radiosurgery for liver malignancies. Int. J. Radiat. Oncol. Biol. Phys. 2005;63:S283
  11. Mackie TR, Holmes T, Swerdloff S, et al. Tomotherapy: A new concept for the delivery of dynamic conformal radiotherapy. Med. Phys. 1993;20:1709–1719
  12. Mackie TR, Balog J, Ruchala K, et al. Tomotherapy. Semin. Radiat. Oncol. 1999;9:108–117
  13. Bauman GB, Yartsev S, Rodrigues G, et al. A prospective evaluation of helical tomotherapy. Int. J. Radiat. Oncol. Biol. Phys. 2007;68:632–641
  14. Ramsey CR, Langen KM, Kupelian PA, et al. A technique for adaptive image-guided helical tomotherapy for lung cancer. Int. J. Radiat. Oncol. Biol. Phys. 2006;64:1237–1244
  15. Ramsey C, Mahan S, Scaperoth D, et al. Image guided adaptive therapy for the treatment of lung cancer. Int. J. Radiat. Oncol. Biol. Phys. 2004;60:S339
  16. Kupelian PA, Ramsey C, Meeks SL, et al. Serial megavoltage CT imaging during external beam radiotherapy for non-small-cell lung cancer: Observations on tumor regression during treatment. Int. J. Radiat. Oncol. Biol. Phys. 2005;63:102–148
  17. Woodford C, Yartsev S, Dar AR, et al. Adaptive radiotherapy planning on decreasing gross tumor volume as seen on megavoltage computed tomography images. Int. J. Radiat. Oncol. Biol. Phys. 2007;69:1316–1322
  18. Yartsev S, Dar AR, Woodford C, et al. Initial experience in treating lung cancer with helical tomotherapy. Biomed. Imaging Interv. J. 2007;3:e2
  19. Sørensen B, Hao J, Overgaard J, et al. Influence of oxygen concentration and pH on expression of hypoxia induced genes. Radiother. Oncol. 2005;76:187–193
  20. Rodrigues G, Lock M, D'Souza D, et al. Prediction of radiation pneumonitis by dose-volume histogram parameters in lung cancer – A systematic review. Radiother. Oncol. 2004;71:127–138
  21. Yartsev S, Chen J, Yu E, et al. Comparative planning evaluation of intensity-modulated radiotherapy techniques for complex lung cancer cases. Radiother. Oncol. 2007;78:169–176
  22. Martel MK, Ten Haken RK, Hazuka MB, et al. Estimation of tumor control probability parameters from 3-D dose distributions of non-small cell lung cancer patients. Lung Cancer. 1999;24:31–37
  23. Saunders M, Dische S, Barrett A, et al. Continuous hyperfractionated accelerated radiotherapy (CHART) versus conventional radiotherapy in non-small cell lung cancer: A randomized multicenter trial. Radiother. Oncol. 1999;52:137–148
  24. Werner-Wasik M, Xiao Y, Pequignot E, et al. Assessment of lung cancer response after nonoperative therapy: Tumor diameter, bidimensional product, and volume (A serial CT scan-based study). Int. J. Radiat. Oncol. Biol. Phys. 2001;51:56–61
  25. Britton KR, Starkschall G, Tucker SL, et al. Assessment of gross tumor volume regression and motion changes during radiotherapy for non small-cell lung cancer as measured by four-dimensional computed tomography. Int. J. Radiat. Oncol. Biol. Phys. 2007;68:1036–1046
  26. Welsh JS, Bradley K, Ruchala KJ, et al. Megavoltage computed tomography imaging: A potential tool to guide and improve the delivery of thoracic radiation therapy. Clin. Lung Cancer. 2004;5:303–306

PII: S0958-3947(08)00164-7

doi: 10.1016/j.meddos.2008.10.002

Medical Dosimetry
Volume 34, Issue 3 , Pages 233-242 , Autumn 2009