Medical Dosimetry
Volume 34, Issue 3 , Pages 250-255 , Autumn 2009

The Effect of Significant Tumor Reduction on the Dose Distribution in Intensity Modulated Radiation Therapy for Head-And-Neck Cancer: A Case Study

Presented in part at the 48th Annual Meeting of the American Society for Therapeutic Radiology and Oncology, Philadelphia, PA, November 5-9, 2006.

  • James Mechalakos, Ph.D.

      Affiliations

    • Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, NY
    • Corresponding Author InformationReprint requests to: James Mechalakos, Ph.D., Memorial Sloan-Kettering Cancer Center, Department of Medical Physics, 1275 York Avenue, New York, NY 10065
    • ,
  • Nancy Lee, M.D.

      Affiliations

    • Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY
    • ,
  • Margie Hunt, M.S.

      Affiliations

    • Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, NY
    • ,
  • C. Clifton Ling, Ph.D.

      Affiliations

    • Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, NY
    • Varian Medical Systems, Palo Alto, CA
    • ,
  • Howard I. Amols, Ph.D.

      Affiliations

    • Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, NY

Received 2 July 2008 ,Accepted 23 October 2008.

References 

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  2. Eisbruch A. Intensity-modulated radiation therapy: A clinical perspective. Semin. Radiat. Oncol. 2002;12:197–198
  3. Nutting C, Dearnaley DP, Webb S. Intensity modulated radiotherapy: A clinical review. Br. J. Radiol. 2000;73:465–469
  4. Mechalakos J, Hunt M, Hong L, et al. Measurement of IMRT head and neck setup error using an on-board kilovotage imager. Int. J. Radiat. Oncol. Biol. Phys. 2005;63:S353–S354
  5. Barker JL, Garden AS, Ang KK, et al. Quantification of volumetric and geometric changes occurring during fractionated radiotherapy for head-and-neck cancer using an integrated CT/linear accelerator system. Int. J. Radiat. Oncol. Biol. Phys. 2004;59:960–970
  6. Kuo Y-C, Wu T-H, Chung T-S, et al. Effect of regression of enlarged neck lymph nodes on radiation doses received by parotid glands during intensity modulated radiotherapy for head and neck cancer. Am. J. Clin. Oncol. 2006;29:600–605
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  13. Meldolesi E, Wu Q, Chen P, et al. Evaluation of anatomic and dosimetric changes during treatment course of head and neck (HN) IMRT: Is replanning necessary?. Int. J. Radiat. Oncol. Biol. Phys. 2006;66:S101–S102
  14. Menon GV, Dunscombe P, Tambasco M. Evaluation of simulator cone beam CT images for radiotherapy treatment planning. Int. J. Radiat. Oncol. Biol. Phys. 2006;66:S689
  15. Niblock P, Sheehan B, Martin M, et al. Volumetric changes in locally advanced head and neck cancer: Is measurement useful?. Radiother. Oncol. 2005;76:S30–S31
  16. Rehbinder H, Lundin A, Sharpe M, et al. Can PTV margins for head and neck cancer be reduced based on a single adaptive replanning event?. Int. J. Radiat. Oncol. Biol. Phys. 2006;66:S101
  17. Wang C, Yang Y, Xing L. Evaluation of cone beam CT (CBCT)-based dose calculation. Int. J. Radiat. Oncol. Biol. Phys. 2006;66:S658
  18. Yoo S, Yin F-F. Dosimetric feasibility of cone beam CT-based treatment planning compared to CT based treatment planning. Int. J. Radiat. Oncol. Biol. Phys. 2006;66:1553–1561

PII: S0958-3947(08)00166-0

doi: 10.1016/j.meddos.2008.10.004

Medical Dosimetry
Volume 34, Issue 3 , Pages 250-255 , Autumn 2009

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