Medical Dosimetry
Volume 35, Issue 1 , Pages 43-48 , Spring 2010

Dosimetric Impact of Intrafractional Patient Motion in Pediatric Brain Tumor Patients

  • Chris Beltran, Ph.D.

      Affiliations

    • Corresponding Author InformationReprint requests to: Chris Beltran, PhD., St. Jude Children's Research Hospital, Radiological Sciences, 262 Danny Thomas Place, MS# 220, Memphis TN 38105
    • ,
  • John Trussell
    • ,
  • Thomas E. Merchant, D.O., Ph.D.

Received 18 September 2008 ,Accepted 12 January 2009.

References 

  1. International Commission on Radiation Units and Measurements. ICRU Report 50: Prescribing, Recording, and Reporting Photon Beam Therapy. Bethesda, MD: ICRU; 1993;
  2. International Commission on Radiation Units and Measurements. ICRU Report 62: Prescribing, Recording, and Reporting Photon Beam Therapy (Supplement to ICRU Report 50. Bethesda, MD). 1999;
  3. Huang E, Teh BS, Strother DR, et al. Intensity-modulated radiation therapy for pediatric medulloblastoma: Early report on the reduction of ototoxicity. Int. J. Radiat. Oncol. Biol. Phys. 2002;52:599–605
  4. Wilson VC, McDonough J, Tochner Z. Proton beam irradiation in pediatric oncology: an overview. J. Pediatr. Hematol. Oncol. 2005;27:444–448
  5. Astreinidou E, Bel A, Raaijmakers CP, et al. Adequate margins for random setup uncertainties in head-and-neck IMRT. Int. J. Radiat. Oncol. Biol. Phys. 2005;61:938–944
  6. Papiez L, Langer M. On probabilistically 170 defined margins in radiation therapy. Phys. Med. Biol. 2006;51:3921–3939
  7. Parker BC, Shiu AS, Maor MH, et al. PTV margin determination in conformal SRT of intracranial lesions. J. Appl. Clin. Med. Phys. 2002;3:176–189
  8. Remeijer P, Rasch C, Lebesque JV, et al. Margins for translational and rotational uncertainties: A 175 probability-based approach. Int. J. Radiat. Oncol. Biol. Phys. 2002;53:464–474
  9. Stroom JC, de Boer HC, Huizenga H, et al. Inclusion of geometrical uncertainties in radiotherapy treatment planning by means of coverage probability. Int. J. Radiat. Oncol. Biol. Phys. 1999;43:905–919
  10. Stroom JC, Heijmen BJ. Geometrical uncertainties, radiotherapy planning margins, and the ICRU-62 report. Radiother. Oncol. 2002;64:75–83
  11. van Herk M, Remeijer P, Rasch C, et al. The probability of correct target dosage: Dose-population histograms for deriving treatment margins in radiotherapy. Int. J. Radiat. Oncol. Biol. Phys. 2000;47:1121–1135
  12. van Herk M, Remeijer P, Lebesque JV. Inclusion of geometric uncertainties in treatment plan evaluation. Int. J. Radiat. Oncol. Biol. Phys. 2002;52:1407–1422
  13. Burton KE, Thomas SJ, Whitney D, et al. Accuracy of a relocatable stereotactic radiotherapy head frame evaluated by use of a depth helmet. Clin. Oncol. (R. Coll. Radiol.). 2002;14:31–39
  14. Humphreys M, Guerrero Urbano MT, Mubata C, et al. Assessment of a customised immobilisation system for head and neck IMRT using electronic portal imaging. Radiother. Oncol. 2005;77:39–44
  15. Linthout N, Verellen D, Tournel K, et al. Six dimensional analysis with daily stereoscopic x-ray imaging of intrafraction patient motion in head and neck treatments using five points fixation masks. Med. Phys. 2006;33:504–513
  16. Suzuki M, Nishimura Y, Nakamatsu K, et al. Analysis of interfractional set-up errors and intrafractional organ motions during IMRT for head and neck tumors to define an appropriate planning target volume (PTV)- and planning organs at risk volume (PRV)-margins. Radiother. Oncol. 2006;78:283–290
  17. Kumar S, Burke K, Nalder C, et al. Treatment accuracy of fractionated stereotactic radiotherapy. Radiother. Oncol. 2005;74:53–59
  18. Coolens C, Evans PM, Seco J, et al. The susceptibility of IMRT dose distributions to intrafraction organ motion: An investigation into smoothing filters derived from four dimensional computed tomography data. Med. Phys. 2006;33:2809–2818
  19. Dawson LA, Brock KK, Kazanjian S, et al. The reproducibility of organ position using active breathing control (ABC) during liver radiotherapy. Int. J. Radiat. Oncol. Biol. Phys. 2001;51:1410–1421
  20. Fung AY, Enke CA, Ayyangar KM. Prostate motion and isocenter adjustment from ultrasound-based localization during delivery of radiation therapy. Int. J. Radiat. Oncol. Biol. Phys. 2005;61:984–992
  21. Herman MG, Pisansky TM, Kruse JJ, et al. Technical aspects of daily online positioning of the prostate for three-dimensional conformal radiotherapy using an electronic portal imaging device. Int. J. Radiat. Oncol. Biol. Phys. 2003;57:1131–1140
  22. Kupelian PA, Willoughby TR, Meeks SL, et al. Intraprostatic fiducials for localization of the prostate gland: Monitoring intermarker distances during radiation therapy to test for marker stability. Int. J. Radiat. Oncol. Biol. Phys. 2005;62:1291–1296
  23. Parker CC, Damyanovich A, Haycocks T. Magnetic resonance imaging in the radiation treatment planning of localized prostate cancer using intra-prostatic fiducial markers for computed tomography co-registration. Radiother. Oncol. 2003;66:217–224
  24. Beltran C, Herman MG, Davis BJ. Planning target margin calculations for prostate radiotherapy based on intrafraction and interfraction motion using four localization methods. Int. J. Radiat. Oncol. Biol. Phys. 2007;70:289–295
  25. Muren LP, Smaaland R, Dahl O. Organ motion, set-up variation and treatment margins in radical radiotherapy of urinary bladder cancer. Radiother. Oncol. 2003;69:291–304
  26. Ekberg L, Holmberg O, Wittgren L, et al. What margins should be added to the clinical target volume in radiotherapy treatment planning for lung cancer?. Radiother. Oncol. 1998;48:71–77
  27. Underberg RW, Lagerwaard FJ, Cuijpers JP, et al. Four dimensional CT scans for treatment planning in stereotactic radiotherapy for stage I lung cancer. Int. J. Radiat. Oncol. Biol. Phys. 2004;60:1283–1290
  28. Underberg RW, Lagerwaard FJ, Slotman BJ, et al. Benefit of respiration-gated stereotactic radiotherapy for stage I lung cancer: An analysis of 4DCT datasets. Int. J. Radiat. Oncol. Biol. Phys. 2005;62:554–560
  29. Zhu Y, Stovall J, Butler L, et al. Comparison of two immobilization techniques using portal film and digitally reconstructed radiographs for pediatric patients with brain tumors. Int. J. Radiat. Oncol. Biol. Phys. 2000;48:1233–1240
  30. Meeks SL, Bova FJ, Wagner TH, et al. Image localization for frameless stereotactic radiotherapy. Int. J. Radiat. Oncol. Biol. Phys. 2000;46:1291–1299
  31. Lujan AE, Ten Haken RK, Larsen EW, et al. Quantization of setup uncertainties in 3-D dose calculations. Med. Phys. 1999;26:2397–2402
  32. Niemierko A. A generalized concept of equivalent uniform dose (EUD). Med. Phys. 1999;26:1100
  33. Siebers JJ, Gordon JV. Evaluation of dosimetric margins in prostate IMRT treatment plans. Med. Phys. 2008;35:569–575
  34. McKenzie A, van Herk M, Mijnheer B. Margins for geometric uncertainty around organs at risk in radiotherapy. Radiother. Oncol. 2002;62:299–307
  35. Stroom JC, Heijmen BJ. Limitations of the planning organ at risk volume (PRV) concept. Int. J. Radiat. Oncol. Biol. Phys. 2006;66:279–286

PII: S0958-3947(09)00006-5

doi: 10.1016/j.meddos.2009.01.004

Medical Dosimetry
Volume 35, Issue 1 , Pages 43-48 , Spring 2010

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