Medical Dosimetry
Volume 36, Issue 3 , Pages 292-298 , Autumn 2011

Comparison of Prostate IMRT and VMAT Biologically Optimised Treatment Plans

  • Nicholas Hardcastle, Ph.D.

      Affiliations

    • Centre for Medical Radiation Physics, University of Wollongong, NSW, Australia
    • Department of Human Oncology and Medical Physics, University of Wisconsin-Madison, WI, USA
    • Corresponding Author InformationReprint requests to: Nicholas Hardcastle, Ph.D., Department of Human Oncology and Medical Physics, School of Medicine and Public Health, University of Wisconsin-Madison, CSC K4/347, 600 Highland Ave., Madison, WI 53792
    • ,
  • Wolfgang A. Tomé, Ph.D.

      Affiliations

    • Centre for Medical Radiation Physics, University of Wollongong, NSW, Australia
    • Department of Human Oncology and Medical Physics, University of Wisconsin-Madison, WI, USA
    • ,
  • Kerwyn Foo, FRANZCR

      Affiliations

    • Centre for Medical Radiation Physics, University of Wollongong, NSW, Australia
    • Illawarra Cancer Care Centre, Wollongong Hospital, Wollongong, NSW, Australia
    • Graduate School of Medicine, University of Wollongong, Wollongong, NSW, Australia
    • ,
  • Andrew Miller, FRANZCR

      Affiliations

    • Illawarra Cancer Care Centre, Wollongong Hospital, Wollongong, NSW, Australia
    • Graduate School of Medicine, University of Wollongong, Wollongong, NSW, Australia
    • ,
  • Martin Carolan, Ph.D.

      Affiliations

    • Illawarra Cancer Care Centre, Wollongong Hospital, Wollongong, NSW, Australia
    • ,
  • Peter Metcalfe, Ph.D.

      Affiliations

    • Centre for Medical Radiation Physics, University of Wollongong, NSW, Australia

Received 8 October 2009 ,Accepted 10 June 2010.

References 

  1. Kupelian PA, Reddy CA, Carlson TP, et al. Preliminary observations on biochemical relapse-free survival rates after short-course intensity-modulated radiotherapy (70 Gy at 2.5 Gy/fraction) for localized prostate cancer. Int. J. Radiat. Oncol. Biol. Phys. 2002;53:904–912
  2. Kupelian PA, Reddy CA, Carlson TP, et al. Dose/volume relationship of late rectal bleeding after external beam radiotherapy for localized prostate cancer: Absolute or relative rectal volume?. Cancer J. 2002;8:62–66
  3. Namiki S, Ishidoya S, Tochigi T, et al. Health-related quality of life after intensity modulated radiation therapy for localized prostate cancer: Comparison with conventional and conformal radiotherapy. Japan. J. Clin. Oncol. 2006;36:224–230
  4. Sanguineti G, Cavey ML, Endres EJ, et al. Does treatment of the pelvic nodes with IMRT increase late rectal toxicity over conformal prostate only radiotherapy to 76 Gy?. Strahlenther. Onkol. 2006;182:543–549
  5. Veldeman L, Madani I, Hulstaert F, et al. Evidence behind use of intensity-modulated radiotherapy: A systematic review of comparative clinical studies. Lancet Oncol. 2008;9:367–375
  6. Zelefsky MJ, Fuks Z, Happersett L, et al. Clinical experience with intensity modulated radiation therapy (IMRT) in prostate cancer. Radiother. Oncol. 2000;55:241–249
  7. Zelefsky MJ, Fuks Z, Hunt M, et al. High dose radiation delivered by intensity modulated conformal radiotherapy improves the outcome of localized prostate cancer. J. Urol. 2001;166:876–881
  8. Bzdusek K, Friberger H, Eriksson K, et al. Development and evaluation of an efficient approach to volumetric arc therapy planning. Med. Phys. 2009;36:2328–2339
  9. Otto K. Volumetric modulated arc therapy: IMRT in a single gantry arc. Med. Phys. 2008;35:310–317
  10. Yu CX. Intensity-modulated arc therapy with dynamic multileaf collimation—an alternative to tomotherapy. Phys. Med. Biol. 1995;40:1435–1449
  11. Palma D, Vollans E, James K, et al. Volumetric modulated arc therapy for delivery of prostate radiotherapy: Comparison with intensity-modulated radiotherapy and three-dimensional conformal radiotherapy. Int. J. Radiat. Oncol. Biol. Phys. 2008;72:996–1001
  12. Palma D, Vollans E, James K, et al. Volumetric modulated arc therapy (VMAT) for delivery of prostate radiotherapy: Reduction in treatment time and monitor unit requirements compared to intensity modulated radiotherapy. 2008;50th Annual Meeting of the American Society for Therapeutic Radiology and Oncology, Boston, MA
  13. Wolff D, Stieler F, Abo-Madyan Y, et al. Volumetric intensity modulated arc therapy (VMAT) vs. serial tomotherapy and segmental (step and shoot) IMRT for treatment of prostate cancer. 2008;50th Annual Meeting of the American Society for Therapeutic Radiology and Oncology, Boston, MA
  14. Wolff D, Stieler F, Welzel G, et al. Volumetric modulated arc therapy (VMAT) vs. serial tomotherapy, step-and-shoot IMRT and 3D-conformal RT for treatment of prostate cancer. Radiother. Oncol. 2009;93:226–233
  15. Zhang P, Happersett L, Hunt M, et al. Volumetric modulated arc therapy: Planning and evaluation for prostate cancer cases. Int. J. Radiat. Oncol. Biol. Phys. 2010;76:1456–1462
  16. Kjaer-Kristoffersen F, Ohlhues L, Medin J, et al. RapidArc volumetric modulated therapy planning for prostate cancer patients. 2008;Symposium of the Nordic Association of Clinical Physics, Arhaus, Denmark
  17. Bortfeld T, Webb S. Single-arc IMRT?. Phys. Med. Biol. 2009;54:N9–N20
  18. Bortfeld T, Webb S. Reply to “Comments on Single-Arc IMRT”?. Phys. Med. Biol. 2009;54:L35–L36
  19. Bortfeld T, Webb S. Reply to letter to the editor on “Single-Arc IMRT”?. Phys. Med. Biol. 2009;54:L43–L44
  20. Otto K. Letter to the editor on “Single-Arc IMRT”?. Phys. Med. Biol. 2009;54:L37–L41
  21. Verbakel W, Senan S, Lagerwaard FJ, et al. Comments on “Single-Arc IMRT”?. Phys. Med. Biol. 2009;54:L31–L34
  22. Kuban DA, Tucker SL, Dong L, et al. Long-term results of the M. D. Anderson randomized dose-escalation trial for prostate cancer. Int. J. Radiat. Oncol. Biol. Phys. 2008;70:67–74
  23. Pollack A, Zagars GK, Starkschall G, et al. Prostate cancer radiation dose response: Results of the M. D. Anderson phase III randomized trial. Int. J. Radiat. Oncol. Biol. Phys. 2002;53:1097–1105
  24. Biological Optimization using the Equivalent Uniform Dose (EUD) in Pinnacle3. Stockholm, Sweden: RaySearch Laboratories AB; 2003;
  25. I.E. Commission (editor). Radiotherapy equipment—coordinates, movements and scales. In IEC1217, 1996, International Electrotechnical Commission.
  26. Feygelman V, Zhang G, Stevens C. Initial dosimetric evaluation of SmartArc—a novel VMAT treatment planning module implemented in a multi-vendor delivery chain. J. Appl. Clin. Med. Phys. 2010;11:99–116
  27. Bortfeld T, Schlegel W, Rhein B. Decomposition of pencil beam kernels for fast dose calculations in 3-dimensional treatment planning. Med. Phys. 1993;20:311–318
  28. McNutt T. Dose calculations: Collapsed cone convolution superposition and delta pixel beam. Philips Healthcare; 2002;
  29. Deasy JO, Blanco AI, Clark VH. CERR: A computational environment for radiotherapy research. Med. Phys. 2003;30:979–985
  30. Kutcher GJ, Burman C. Calculation of complication probability factors for non-uniform normal tissue irradiation—the effective volume method. Int. J. Radiat. Oncol. Biol. Phys. 1989;16:1623–1630
  31. Lyman JT. Complication probability as assessed from dose volume histograms. Radiat. Res. 1985;104:S13–S19
  32. Tucker SL, Dong L, Cheung R, et al. Comparison of rectal dose-wall histogram versus dose-volume histogram for modeling the incidence of late rectal bleeding after radiotherapy. Int. J. Radiat. Oncol. Biol. Phys. 2004;60:1589–1601
  33. Tucker SL, Dong L, Bosch WR, et al. Fit of a generalized Lyman normal-tissue complication probability (NTCP) model to grade >= 2 late rectal toxicity data from patients treated on protocol RTOG 94-06. 2007;49th Annual Meeting of the American Society for Therapeutic Radiology and Oncology, Los Angeles, CA
  34. Rancati T, Fiorino C, Gagliardi G, et al. Fitting late rectal bleeding data using different NTCP models: Results from an Italian multi-centric study (AIROPROS0101). Radiother. Oncol. 2004;73:21–32
  35. Ost P, Fonteyne V, De Neve W, et al. Volumetric modulated arc therapy for delivery of prostate radiotherapy. (In regard to Palma, D.; et al. Int. J. Radiat. Oncol. Biol. Phys. 70:996–1001; 2008) Int. J. Radiat. Oncol. Biol. Phys. 2009;73:1286
  36. Palma D, Moiseenko V, Vollans E, et al. Volumetric modulated arc therapy for delivery of prostate radiotherapy: Reply to Palma, D. et al. Int. J. Radiat. Oncol. Biol. Phys. 70: 996–1001; 2008). Int. J. Radiat. Oncol. Biol. Phys. 2009;73:1287
  37. Sohn M, Yan D, Liang J, et al. Incidence of late rectal bleeding in high-dose conformal radiotherapy of prostate cancer using equivalent uniform dose-based and dose-volume-based normal tissue complication probability models. Int. J. Radiat. Oncol. Biol. Phys. 2007;67:1066–1073

PII: S0958-3947(10)00071-3

doi: 10.1016/j.meddos.2010.06.001

Medical Dosimetry
Volume 36, Issue 3 , Pages 292-298 , Autumn 2011

Article Tools

* Image Usage & Resolution