Abstract
Whole-pelvis pencil beam scanning (PBS) proton therapy is utilized in both the intact
and post-operative settings in patients with prostate cancer. As whole pelvis prostate
radiotherapy has traditionally been delivered with standard photon beams, limited
evidence and technical descriptions have been reported regarding the use of proton
therapy. Here we present two robust three-field treatment planning approaches utilized
to maximize target coverage in the presence of anatomic and delivery uncertainties.
Both techniques, conventional optimization (CO) and robust optimization (RO), create
treatment plans with acceptable target coverage and sparing of organs at risk (OAR).
While the RO method is less time intensive and may theoretically allow for superior
OAR sparing and improved robustness, the CO method can be implemented by institutions
who do not have RO capabilities.
Keywords
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Article info
Publication history
Published online: May 26, 2020
Accepted:
April 6,
2020
Received in revised form:
March 30,
2020
Received:
February 18,
2020
Footnotes
Meeting: Poster Presentation, Particle Therapy Cooperative Oncology Group North America Sixth Annual Conference, October 14-16, 2019, Miami, FL.
Identification
Copyright
© 2020 American Association of Medical Dosimetrists. Published by Elsevier Inc. All rights reserved.
